Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.42 |
| ▸ | THRA | P10827 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | DPYD | Q12882 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5308604 | 0.90 | MEN1 (0.43) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5308388 | 0.89 | THRA (0.48) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5312251 | 0.84 | MEN1 (0.48) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5312400 | 0.84 | MEN1 (0.48) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL15846440 | 0.83 | HIF1A (0.49) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5312539 | 0.81 | MEN1 (0.46) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL15846776 | 0.81 | MEN1 (0.56) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5309396 | 0.78 | EGLN1 (0.43) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL15846836 | 0.78 | MEN1 (0.40) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL15845949 | 0.78 | MEN1 (0.43) | MEN1KMT2ARXFP1NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | claimed |