Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HK1 | P19367 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5308453 | 0.99 | MAPT (0.47) | MAPTPTGDR2HSD17B10ALDH1A1CA12 | |
| SCHEMBL1757609 | 0.84 | MAPT (0.48) | MAPTPTGDR2HSD17B10ALDH1A1LMNA | |
| SCHEMBL5310459 | 0.80 | MAPT (0.45) | MAPTPTGDR2HSD17B10ALDH1A1CA12 | |
| SCHEMBL5314252 | 0.78 | PTGDR2 (0.47) | MAPTPTGDR2ALDH1A1CA12CA1 | |
| SCHEMBL5310070 | 0.77 | CA12 (0.43) | MAPTPTGDR2HSD17B10ALDH1A1CA12 | |
| SCHEMBL1758023 | 0.77 | PTGDR2 (0.49) | MAPTPTGDR2HSD17B10ALDH1A1LMNA | |
| SCHEMBL1757624 | 0.76 | PTGDR2 (0.51) | MAPTPTGDR2HSD17B10ALDH1A1LMNA | |
| SCHEMBL5313192 | 0.76 | PTGDR2 (0.48) | MAPTPTGDR2ALDH1A1CA12CA1 | |
| SCHEMBL5311262 | 0.76 | PTGDR2 (0.47) | MAPTPTGDR2ALDH1A1CA12CA1 | |
| SCHEMBL1757971 | 0.75 | PTGDR2 (0.50) | MAPTPTGDR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045867-A1 | 3 -AMINOINDOLE COMPOUNDS AS CRTH2 RECEPTOR LIGANDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-04-26 | — | — | WO | disclosed |