SCHEMBL5310070 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	CA12	O43570	1/20	0.43

▸	CA1	P00915	1/20	0.43

▸	CA2	P00918	1/20	0.43

▸	CA9	Q16790	1/20	0.43

▸	ALDH1A1	P00352	2/20	0.43

▸	USP2	O75604	1/20	0.43

▸	ACLY	P53396	4/20	0.43

▸	MAPT	P10636	1/20	0.43

▸	PTGDR2	Q9Y5Y4	7/20	0.42

▸	AKR1B1	P15121	1/20	0.42

▸	FLT1	P17948	1/20	0.40

▸	FLT4	P35916	1/20	0.40

▸	KDR	P35968	1/20	0.40

▸	HSD17B10	Q99714	1/20	0.39

▸	LOXL2	Q9Y4K0	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5314252	0.92	PTGDR2 (0.47)	CA12CA1CA2CA9ALDH1A1
SCHEMBL5311262	0.89	PTGDR2 (0.47)	CA12CA1CA2CA9ALDH1A1
SCHEMBL5313741	0.89	PTGDR2 (0.54)	ACLYPTGDR2AKR1B1
SCHEMBL5313784	0.88	USP2 (0.45)	CA12CA1CA2CA9ALDH1A1
SCHEMBL5307807	0.88	PTGDR2 (0.50)	CA12CA1CA2CA9ALDH1A1
SCHEMBL5312658	0.86	MAPT (0.51)	CA12CA1CA2CA9ALDH1A1
SCHEMBL5310476	0.86	ALDH1A1 (0.46)	CA12CA1CA2CA9ALDH1A1
SCHEMBL5307689	0.86	PTGDR2 (0.46)	CA12CA1CA2CA9ALDH1A1
SCHEMBL5313192	0.85	PTGDR2 (0.48)	CA12CA1CA2CA9ALDH1A1
SCHEMBL5312227	0.82	CCR4 (0.46)	MAPTPTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2007045867-A1	3 -AMINOINDOLE COMPOUNDS AS CRTH2 RECEPTOR LIGANDS	ARGENTA DISCOVERY LIMITED (GB)	2007-04-26	—	—	WO	disclosed