Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5308988 | 1.00 | CA1 (0.51) | CA1CA2MEN1KMT2APLA2G7 | |
| SCHEMBL5300670 | 0.80 | NPC1 (0.55) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5300668 | 0.80 | NPC1 (0.55) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3462265 | 0.79 | MAPT (0.44) | CA1CA2MEN1KMT2APLA2G7 | |
| SCHEMBL887447 | 0.79 | MAPT (0.44) | CA1CA2MEN1KMT2APLA2G7 | |
| SCHEMBL10056240 | 0.79 | MAPT (0.44) | CA1CA2MEN1KMT2APLA2G7 | |
| SCHEMBL27976196 | 0.79 | MEN1 (0.54) | MEN1KMT2APLA2G7RAB9ANPC1 | |
| SCHEMBL5294665 | 0.79 | NPC1 (0.53) | MEN1KMT2ARAB9ANPC1FAAH | |
| SCHEMBL5294662 | 0.79 | NPC1 (0.53) | MEN1KMT2ARAB9ANPC1FAAH | |
| SCHEMBL11167912 | 0.78 | CA1 (0.46) | CA1CA2MEN1KMT2APLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011910-A2 | CHIRAL AMINE-CATALYZED ASYMMETRIC ADDITION OF CARBON-CENTERED NUCLEOPHILES TO IMINES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2007-01-25 | — | — | WO | disclosed |