Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10056240 | 1.00 | MAPT (0.44) | MAPTMIFPLA2G7RAB9ANPC1 | |
| SCHEMBL887447 | 1.00 | MAPT (0.44) | MAPTMIFPLA2G7RAB9ANPC1 | |
| SCHEMBL29219514 | 0.84 | MIF (0.45) | MAPTMIFRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27959813 | 0.83 | CYP2C19 (0.39) | MAPTPLA2G7RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29219426 | 0.83 | MIF (0.44) | MAPTMIFPLA2G7RAB9ANPC1 | |
| SCHEMBL29846226 | 0.83 | MIF (0.44) | MAPTMIFPLA2G7RAB9ANPC1 | |
| SCHEMBL29219498 | 0.83 | NPC1 (0.61) | MAPTMIFRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29219460 | 0.83 | CA2 (0.48) | MAPTMIFRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20521947 | 0.83 | MIF (0.44) | MAPTMIFRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17302200 | 0.83 | NPC1 (0.61) | MAPTMIFRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101538226-A | Method for synthesizing optically active alpha-hydroxyl-beta-phenmethyl-beta-amino acid derivative | UNIV EAST CHINA NORMAL | 2009-09-23 | — | — | CN | claimed |
| US-12486232-B2 | Method for preparing meta-functionalized pyridine compound | NANKAI UNIVERSITY (CN) | 2025-12-02 | — | — | US | disclosed |
| US-20250179021-A1 | Method For Preparing Meta-Functionalized Pyridine Compound | CNBM RESEARCH INSTITUTE FOR ADVANCED GLASS MATERIALS GROUP CO., LTD. (CN) | 2025-06-05 | — | — | US | disclosed |
| CN-117946023-A | Preparation method of trans-4, 5-disubstituted oxazolidone compound | 南京工业大学 | 2024-04-30 | — | — | CN | disclosed |
| WO-2023039975-A1 | METHOD FOR PREPARING META-FUNCTIONALIZED PYRIDINE COMPOUND | 南开大学 | 2023-03-23 | — | — | WO | disclosed |
| CN-110845288-B | Asymmetric synthesis method of chiral beta-amino aldehyde compound | 浙江工业大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-113527188-B | Method for preparing meta-functionalized pyridine compound | 南开大学 | 2021-11-26 | — | — | CN | disclosed |
| CN-113527188-A | Method for preparing meta-functionalized pyridine compound | 南开大学 | 2021-10-22 | — | — | CN | disclosed |
| CN-109046449-B | Tertiary amine-thiourea bifunctional chiral catalyst and preparation method and application thereof | 石家庄学院 | 2021-04-06 | — | — | CN | disclosed |
| CN-110845288-A | Asymmetric synthesis method of chiral β -amino aldehyde compound | 浙江工业大学 | 2020-02-28 | — | — | CN | disclosed |
| US-20120330038-A1 | BIS-PHOSPHATE COMPOUND AND ASYMMETRIC REACTION USING THE SAME | API CORPORATION (JP) | 2012-12-27 | — | — | US | disclosed |
| US-20100298559-A1 | OPTICALLY ACTIVE DINICKEL COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE USING THE OPTICALLY ACTIVE DINICKEL COMPLEX AS CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-11-25 | — | — | US | disclosed |
| US-20100298559-A1 | OPTICALLY ACTIVE DINICKEL COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE USING THE OPTICALLY ACTIVE DINICKEL COMPLEX AS CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-11-25 | — | — | US | disclosed |
| EP-2233468-A1 | OPTICALLY ACTIVE DINICKEL COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE USING THE OPTICALLY ACTIVE DINICKEL COMPLEX AS CATALYST | Nissan Chemical Industries, Ltd. (JP) | 2010-09-29 | — | — | EP | disclosed |
| CN-101538226-A | Method for synthesizing optically active alpha-hydroxyl-beta-phenmethyl-beta-amino acid derivative | UNIV EAST CHINA NORMAL | 2009-09-23 | — | — | CN | disclosed |
| CN-101362100-A | Chiral amine-(sulphur)urea double functional catalyst and synthesis method and use thereof | UNIV FUDAN (CN) | 2009-02-11 | — | — | CN | disclosed |
| US-6114550-A | Method for the stereo-selective preparation of a derivative of β-phenyl-isoserine and its use in the preparation of taxane derivatives | RHONE-POULENC RORER S.A. (FR) | 2000-09-05 | — | — | US | disclosed |
| US-5811550-A | Process for the preparation of a 1,3-oxazolidine-5-carboxylic acid | RHONE-POULENC RORER, S.A. (FR) | 1998-09-22 | — | — | US | disclosed |
| US-5726346-A | Process for the stereoselective preparation of a β-phenylisoserine derivative and its use for the preparation of taxane derivatives | RHONE-POULENC RORER S.A. (FR) | 1998-03-10 | — | — | US | disclosed |
| US-5637753-A | Process for the preparation of N-carbonylarylimines useful in the synthesis of therapeutically active taxoids | RHONE-POULENC RORER S.A. (FR) | 1997-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298559-A1 | OPTICALLY ACTIVE DINICKEL COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE USING THE OPTICALLY ACTIVE DINICKEL COMPLEX AS CATALYST | C5, C9, CCNE1 | MAPT 3244/4885MIF 3701/4885PLA2G7 2752/4885 |
| US-20120330038-A1 | BIS-PHOSPHATE COMPOUND AND ASYMMETRIC REACTION USING THE SAME | AASDHPPT, ALDH7A1, ATIC | MAPT 1467/4885MIF 3412/4885PLA2G7 915/4885 |
| US-12486232-B2 | Method for preparing meta-functionalized pyridine compound | GAPVD1, SKP1, PDXK | MAPT 2134/4885MIF 1713/4885PLA2G7 4004/4885 |
| US-20250179021-A1 | Method For Preparing Meta-Functionalized Pyridine Compound | GAPVD1, SKP1, PDXK | MAPT 2134/4885MIF 1713/4885PLA2G7 4004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.