Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10056240 | 1.00 | MAPT (0.44) | MAPTMIFPLA2G7RAB9ANPC1 | |
| SCHEMBL3462265 | 1.00 | MAPT (0.44) | MAPTMIFPLA2G7RAB9ANPC1 | |
| SCHEMBL29219514 | 0.84 | MIF (0.45) | MAPTMIFRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27959813 | 0.83 | CYP2C19 (0.39) | MAPTPLA2G7RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29219426 | 0.83 | MIF (0.44) | MAPTMIFPLA2G7RAB9ANPC1 | |
| SCHEMBL29846226 | 0.83 | MIF (0.44) | MAPTMIFPLA2G7RAB9ANPC1 | |
| SCHEMBL29219498 | 0.83 | NPC1 (0.61) | MAPTMIFRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29219460 | 0.83 | CA2 (0.48) | MAPTMIFRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20521947 | 0.83 | MIF (0.44) | MAPTMIFRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17302200 | 0.83 | NPC1 (0.61) | MAPTMIFRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110845288-B | Asymmetric synthesis method of chiral beta-amino aldehyde compound | 浙江工业大学 | 2022-07-19 | — | — | CN | disclosed |
| WO-2021021699-A1 | TARGETED NITROXIDE COMPOUNDS AND THEIR USE IN TREATING FERROPTOSIS-RELATED DISEASES | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-02-04 | — | — | WO | disclosed |
| EP-2861559-B1 | METHOD AND CATALYST FOR SYNTHESISING AZIRIDINE | UNIV OF EAST ANGLIA (GB) | 2020-09-16 | — | — | EP | disclosed |
| CN-110845288-A | Asymmetric synthesis method of chiral β -amino aldehyde compound | 浙江工业大学 | 2020-02-28 | — | — | CN | disclosed |
| US-10259784-B2 | Method and catalyst for synthesising aziridine | UNIVERSITY OF EAST ANGLIA (GB) | 2019-04-16 | — | — | US | disclosed |
| US-20170342030-A1 | METHOD AND CATALYST FOR SYNTHESISING AZIRIDINE | UNIV OF EAST ANGLIA (GB) | 2017-11-30 | — | — | US | disclosed |
| US-20170342030-A1 | METHOD AND CATALYST FOR SYNTHESISING AZIRIDINE | UNIV OF EAST ANGLIA (GB) | 2017-11-30 | — | — | US | disclosed |
| US-20170283411-A1 | Optically Active a-Trifluoromethyl-B-Amino Acid Derivative Production Method | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2017-10-05 | — | — | US | disclosed |
| US-9732034-B2 | Method and catalyst for synthesising aziridine | UNIVERSITY OF EAST ANGLIA (GB) | 2017-08-15 | — | — | US | disclosed |
| US-9732034-B2 | Method and catalyst for synthesising aziridine | UNIVERSITY OF EAST ANGLIA (GB) | 2017-08-15 | — | — | US | disclosed |
| EP-2233468-A1 | OPTICALLY ACTIVE DINICKEL COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE USING THE OPTICALLY ACTIVE DINICKEL COMPLEX AS CATALYST | Nissan Chemical Industries, Ltd. (JP) | 2010-09-29 | — | — | EP | disclosed |
| EP-2233468-A1 | OPTICALLY ACTIVE DINICKEL COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE USING THE OPTICALLY ACTIVE DINICKEL COMPLEX AS CATALYST | Nissan Chemical Industries, Ltd. (JP) | 2010-09-29 | — | — | EP | disclosed |
| US-20100185000-A1 | TITANIUM COMPOUND AND PROCESS FOR ASYMMETRIC CYANATION OF IMINES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-07-22 | — | — | US | disclosed |
| US-20100185000-A1 | TITANIUM COMPOUND AND PROCESS FOR ASYMMETRIC CYANATION OF IMINES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-07-22 | — | — | US | disclosed |
| EP-2208722-A1 | PROCESS FOR PRODUCTION OF DISULFONIC ACID COMPOUND, ASYMMETRIC MANNICH CATALYST, PROCESS FOR PRODUCTION OF -AMINOCARBONYL DERIVATIVE, AND NOVEL DISULFONATE SALT | National University Corporation Nagoya University (JP) | 2010-07-21 | — | — | EP | disclosed |
| CN-101466729-A | Lysobactin amides | AICURIS GMBH & CO KG (DE) | 2009-06-24 | — | — | CN | disclosed |
| WO-2009041919-A1 | TITANIUM COMPOUND AND PROCESS FOR ASYMMETRIC CYANATION OF IMINES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2009-04-02 | — | — | WO | disclosed |
| WO-2008121076-A1 | TITANIUM COMPOUND AND PROCESS FOR ASYMMETRIC CYANATION OF IMINES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-10-09 | — | — | WO | disclosed |
| US-20070142639-A1 | Process for production of amines | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-06-21 | — | — | US | disclosed |
| US-20070142639-A1 | Process for production of amines | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10259784-B2 | Method and catalyst for synthesising aziridine | ITPA, PPA1, PPIP5K2 | MAPT 4716/4885MIF 2973/4885PLA2G7 460/4885 |
| US-20100185000-A1 | TITANIUM COMPOUND AND PROCESS FOR ASYMMETRIC CYANATION OF IMINES | ABL1, CD59, TDO2 | MAPT 3880/4885MIF 982/4885PLA2G7 3852/4885 |
| US-20070142639-A1 | Process for production of amines | SMS, CCNT1, PEAK1 | MAPT 1941/4885MIF 4743/4885PLA2G7 662/4885 |
| US-20170342030-A1 | METHOD AND CATALYST FOR SYNTHESISING AZIRIDINE | ITPA, PPA1, PPIP5K2 | MAPT 4716/4885MIF 2973/4885PLA2G7 460/4885 |
| US-20170283411-A1 | Optically Active a-Trifluoromethyl-B-Amino Acid Derivative Production Method | BCAT1, BCAT2, ALAD | MAPT 2460/4885MIF 4192/4885PLA2G7 870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.