Piperine

Piperine

SCHEMBL5309092

O=C(/C=C/C=C/c1ccc2c(c1)OCO2)N1CCCCC1.O=C(/C=C/C=C/c1ccc2c(c1)OCO2)N1CCCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 1.00
HPGD P15428 4/20 1.00
KDM4E B2RXH2 4/20 1.00
ALDH1A1 P00352 4/20 1.00
HSD17B10 Q99714 3/20 1.00
TRPV1 Q8NER1 3/20 1.00
CYP3A4 P08684 2/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
NPC1 O15118 2/20 1.00
RAB9A P51151 2/20 1.00
GABRA1 P14867 2/20 1.00
GABRB2 P47870 2/20 1.00
CYP1A2 P05177 2/20 1.00
ALOX5 P09917 2/20 1.00
HDAC6 Q9UBN7 2/20 1.00
CTSD P07339 1/20 1.00
ABCB1 P08183 1/20 1.00
MAOA P21397 1/20 1.00
MAPK1 P28482 1/20 1.00
DHODH Q02127 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperine SCHEMBL11434404 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10
Piperine SCHEMBL94058 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10
Piperine SCHEMBL29370397 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10
Piperine SCHEMBL29369346 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10
SCHEMBL17340450 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10
Piperine SCHEMBL14171509 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10
Piperine SCHEMBL13151642 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10
Piperine SCHEMBL119081 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10
Piperine SCHEMBL29358781 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10
Piperine SCHEMBL94059 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11062794-B2 Olfactory signature and odorant mixture having the same YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-07-13 US disclosed
WO-2019051565-A1 COMPOSITION AND USES THEREOF BH Biotech Pty Ltd (AU) 2019-03-21 WO disclosed
US-20180253534-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2018-09-06 US disclosed
WO-2014128724-A1 ANTITUBERCULAR COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-08-28 WO disclosed
WO-2013035070-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2013-03-14 WO disclosed
CN-102369177-A Use of nitrogen-containing curcumin analogs for the treatment alzheimer's disease CODMAN & SHURTLEFF 2012-03-07 CN disclosed
WO-2007038524-A2 COCRYSTALLIZATION METHODS SSCI, INC. (US) 2007-04-05 WO disclosed