Piperine

Piperine

SCHEMBL29370397

O=C(/C=C\C=C/c1ccc2c(c1)OCO2)N1CCCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 1.00
HPGD P15428 4/20 1.00
KDM4E B2RXH2 4/20 1.00
ALDH1A1 P00352 4/20 1.00
HSD17B10 Q99714 3/20 1.00
TRPV1 Q8NER1 3/20 1.00
CYP3A4 P08684 2/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
NPC1 O15118 2/20 1.00
RAB9A P51151 2/20 1.00
GABRA1 P14867 2/20 1.00
GABRB2 P47870 2/20 1.00
CYP1A2 P05177 2/20 1.00
ALOX5 P09917 2/20 1.00
HDAC6 Q9UBN7 2/20 1.00
CTSD P07339 1/20 1.00
ABCB1 P08183 1/20 1.00
MAOA P21397 1/20 1.00
MAPK1 P28482 1/20 1.00
DHODH Q02127 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperine SCHEMBL11434404 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10
Piperine SCHEMBL94058 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10
Piperine SCHEMBL29369346 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10
Piperine SCHEMBL5309092 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10
SCHEMBL17340450 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10
Piperine SCHEMBL14171509 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10
Piperine SCHEMBL13151642 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10
Piperine SCHEMBL119081 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10
Piperine SCHEMBL29358781 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10
Piperine SCHEMBL94059 1.00 MAOB (1.00) MAOBHPGDKDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3265606-B1 FIBROUS ELEMENTS, FIBROUS STRUCTURES, AND PRODUCTS COMPRISING A DETERRENT AGENT AND METHODS FOR MAKING SAME PROCTER & GAMBLE (US) 2025-06-04 EP claimed
US-20240285629-A1 Combination Therapy for Use in Treating Retroviral Infections CIPLA LIMITED (IN) 2024-08-29 US claimed
EP-3525825-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING RIFAXIMIN CIPLA LTD (IN) 2024-03-20 EP claimed
EP-3494104-B1 WARMING SENSATION COMPOUNDS TAKASAGO PERFUMERY CO LTD (JP) 2023-11-15 EP claimed
EP-3463326-B1 COMPOSITIONS AND METHODS FOR IMPROVING HYDRATION OF INDIVIDUALS HAVING DYSPHAGIA NESTLE SA (CH) 2023-09-20 EP claimed
EP-4229639-A1 METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE GBS Global Biopharma, Inc. (CA) 2023-08-23 EP claimed
US-20230119206-A1 COMPOSITIONS COMPRISING IBRUTINIB AND AN ALKALOID HAVING ENHANCED BIOAVAILABILITY CIPLA LIMITED (IN) 2023-04-20 US claimed
US-20220193043-A1 Pharmaceutical Combination Formulations Comprising Tizanidine, Resveratrol and Piperine CIPLA LIMITED (IN) 2022-06-23 US claimed
WO-2022081889-A1 METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE GBS GLOBAL BIOPHARMA, INC. (CA) 2022-04-21 WO claimed
US-20220110938-A1 Combination Therapy for Use in Treating Retroviral Infections CIPLA LIMITED (IN) 2022-04-14 US claimed
EP-3946267-A1 PHARMACEUTICAL COMBINATION FORMULATIONS COMPRISING TIZANIDINE, RESVERATROL AND PIPERINE Cipla Limited (IN) 2022-02-09 EP claimed
US-11234981-B2 Combination therapy for use in treating retroviral infections CIPLA LIMITED (IN) 2022-02-01 US claimed
EP-3525825-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING RIFAXIMIN CIPLA LTD (IN) 2024-03-20 EP disclosed
CN-110087688-B Pharmaceutical composition comprising rifaximin 希普拉有限公司 2023-05-05 CN disclosed
US-20230119206-A1 COMPOSITIONS COMPRISING IBRUTINIB AND AN ALKALOID HAVING ENHANCED BIOAVAILABILITY CIPLA LIMITED (IN) 2023-04-20 US disclosed
US-11612612-B2 Pharmaceutical compositions CIPLA LIMITED (IN) 2023-03-28 US disclosed
EP-4025700-A1 NUCLEIC ACIDS, PROTEINS AND PROCESSES FOR PRODUCING PIPERINE AND OTHER AMIDES Leibniz-Institut für Pflanzenbiochemie (IPB) (DE) 2022-07-13 EP disclosed
US-20220130493-A1 METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE GBS GLOBAL BIOPHARMA, INC. (CA) 2022-04-28 US disclosed
WO-2022081889-A1 METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE GBS GLOBAL BIOPHARMA, INC. (CA) 2022-04-21 WO disclosed
US-11267798-B2 Process for the preparation of piperine CIPLA LIMITED (IN) 2022-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11612612-B2 Pharmaceutical compositions HAVCR2, APOB, ABCB11 MAOB 772/4885HPGD 1205/4885KDM4E 3672/4885
US-20230119206-A1 COMPOSITIONS COMPRISING IBRUTINIB AND AN ALKALOID HAVING ENHANCED BIOAVAILABILITY BCL6B, BCL9, BCL6 MAOB 1034/4885HPGD 2887/4885KDM4E 1527/4885
US-11234981-B2 Combination therapy for use in treating retroviral infections PAICS, HAVCR2, THPO MAOB 730/4885HPGD 2355/4885KDM4E 4050/4885
US-20220193043-A1 Pharmaceutical Combination Formulations Comprising Tizanidine, Resveratrol and Piperine CPT1B, GABRR2, SLC6A11 MAOB 1988/4885HPGD 577/4885KDM4E 1055/4885
US-11267798-B2 Process for the preparation of piperine PTMA, ITPA, PRPH MAOB 996/4885HPGD 1264/4885KDM4E 2056/4885
US-20220110938-A1 Combination Therapy for Use in Treating Retroviral Infections PAICS, HAVCR2, THPO MAOB 730/4885HPGD 2355/4885KDM4E 4050/4885
US-20240285629-A1 Combination Therapy for Use in Treating Retroviral Infections PAICS, HAVCR2, THPO MAOB 730/4885HPGD 2355/4885KDM4E 4050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.