Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.71 |
| ▸ | CA9 | Q16790 | 8/20 | 0.71 |
| ▸ | CA1 | P00915 | 8/20 | 0.71 |
| ▸ | CA7 | P43166 | 2/20 | 0.71 |
| ▸ | PTGS2 | P35354 | 16/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.70 |
| ▸ | CA12 | O43570 | 6/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309135 | 1.00 | CA2 (0.71) | CA2CA9CA1CA7PTGS2 | |
| SCHEMBL5312579 | 0.91 | CA2 (0.71) | CA2CA9CA1CA7PTGS2 | |
| SCHEMBL5312581 | 0.91 | CA2 (0.71) | CA2CA9CA1CA7PTGS2 | |
| SCHEMBL5309207 | 0.85 | PTGS2 (0.81) | CA2CA9CA1CA7PTGS2 | |
| SCHEMBL5309203 | 0.85 | PTGS2 (0.81) | CA2CA9CA1CA7PTGS2 | |
| SCHEMBL5312743 | 0.83 | PTGS2 (1.00) | CA2CA9CA1CA7PTGS2 | |
| SCHEMBL5309673 | 0.83 | PTGS2 (1.00) | CA2CA9CA1CA7PTGS2 | |
| SCHEMBL5312741 | 0.83 | PTGS2 (1.00) | CA2CA9CA1CA7PTGS2 | |
| SCHEMBL5309671 | 0.83 | PTGS2 (1.00) | CA2CA9CA1CA7PTGS2 | |
| SCHEMBL5309663 | 0.81 | PTGS2 (0.74) | CA2CA9CA1CA7PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799823-B1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | DAIICHI SANKYO CO LTD (JP) | 2007-10-31 | — | — | EP | disclosed |
| US-RE39420-E1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | SANKYO COMPANY, LIMITED (JP) | 2006-12-05 | — | — | US | disclosed |
| US-5908858-A | OSTEOPOROSIS; LEUKOTRIENE INHIBITOR | SANKYO COMPANY, LIMITED (JP) | 1999-06-01 | — | — | US | disclosed |
| EP-0799823-A1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1997-10-08 | — | — | EP | disclosed |