Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5308815 | 0.92 | APOBEC3A (0.33) | APOBEC3AAPOBEC3GMEN1KMT2AHTT | |
| SCHEMBL5311331 | 0.92 | MAPT (0.34) | APOBEC3AAPOBEC3GMEN1KMT2AHTT | |
| SCHEMBL5309825 | 0.92 | IRAK4 (0.36) | APOBEC3AAPOBEC3GMEN1KMT2AMAPT | |
| SCHEMBL5310044 | 0.91 | MEN1 (0.39) | APOBEC3AAPOBEC3GMEN1KMT2AHTT | |
| SCHEMBL5306949 | 0.91 | APOBEC3A (0.38) | APOBEC3AAPOBEC3GMEN1KMT2AMAPT | |
| SCHEMBL14542210 | 0.91 | CA12 (0.41) | MEN1KMT2AMAPTPOLBRXFP1 | |
| SCHEMBL5313987 | 0.87 | HPGD (0.34) | APOBEC3AAPOBEC3GMEN1KMT2AMAPT | |
| SCHEMBL5309338 | 0.87 | IRAK4 (0.38) | APOBEC3AAPOBEC3GMEN1KMT2AMAPT | |
| SCHEMBL5309667 | 0.85 | APOBEC3A (0.34) | APOBEC3AAPOBEC3GMEN1KMT2AALDH1A1 | |
| SCHEMBL5306763 | 0.85 | HPGD (0.35) | APOBEC3AAPOBEC3GMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039146-A1 | 4-CARBOXY PYRAZOLE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-12 | — | — | WO | claimed |
| WO-2007039146-A1 | 4-CARBOXY PYRAZOLE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007039146-A1 | 4-CARBOXY PYRAZOLE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-12 | — | — | WO | disclosed |