Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | AURKA | O14965 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309338 | 0.92 | IRAK4 (0.38) | MEN1KMT2AMAPTAPOBEC3AAPOBEC3G | |
| SCHEMBL5309593 | 0.92 | HPGD (0.39) | MEN1KMT2AMAPTAPOBEC3AAPOBEC3G | |
| SCHEMBL5309170 | 0.91 | APOBEC3A (0.34) | MEN1KMT2AHTTMAPTPOLB | |
| SCHEMBL5311331 | 0.90 | MAPT (0.34) | MEN1KMT2AHTTMAPTPOLB | |
| SCHEMBL5308815 | 0.90 | APOBEC3A (0.33) | MEN1KMT2AHTTMAPTPOLB | |
| SCHEMBL5310626 | 0.89 | ALKBH5 (0.36) | APOBEC3AAPOBEC3G | |
| SCHEMBL5312693 | 0.88 | APOBEC3A (0.35) | MEN1KMT2AMAPTAPOBEC3AAPOBEC3G | |
| SCHEMBL5306834 | 0.88 | PDE4A (0.37) | MEN1KMT2AMAPTPOLBAPOBEC3A | |
| SCHEMBL5306949 | 0.86 | APOBEC3A (0.38) | MEN1KMT2AMAPTPOLBAPOBEC3A | |
| SCHEMBL5313987 | 0.86 | HPGD (0.34) | MEN1KMT2AMAPTPOLBAPOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039146-A1 | 4-CARBOXY PYRAZOLE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-12 | — | — | WO | claimed |