Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306763 | 0.92 | HPGD (0.35) | MAPTPOLBAPOBEC3AAPOBEC3GMEN1 | |
| SCHEMBL5309170 | 0.92 | APOBEC3A (0.34) | MAPTPOLBAPOBEC3AAPOBEC3GMEN1 | |
| SCHEMBL5308815 | 0.91 | APOBEC3A (0.33) | MAPTPOLBAPOBEC3AAPOBEC3GMEN1 | |
| SCHEMBL5312653 | 0.90 | APOBEC3A (0.35) | MAPTAPOBEC3AAPOBEC3GMEN1KMT2A | |
| SCHEMBL5310044 | 0.90 | MEN1 (0.39) | MAPTPOLBAPOBEC3AAPOBEC3GMEN1 | |
| SCHEMBL5313987 | 0.89 | HPGD (0.34) | MAPTPOLBAPOBEC3AAPOBEC3GMEN1 | |
| SCHEMBL5312693 | 0.86 | APOBEC3A (0.35) | MAPTAPOBEC3AAPOBEC3GMEN1KMT2A | |
| SCHEMBL5309593 | 0.86 | HPGD (0.39) | MAPTAPOBEC3AAPOBEC3GMEN1KMT2A | |
| SCHEMBL5311722 | 0.86 | HPGD (0.34) | MAPTAPOBEC3AAPOBEC3GMEN1KMT2A | |
| SCHEMBL5309825 | 0.85 | IRAK4 (0.36) | MAPTAPOBEC3AAPOBEC3GMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039146-A1 | 4-CARBOXY PYRAZOLE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007039146-A1 | 4-CARBOXY PYRAZOLE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-12 | — | — | WO | disclosed |