Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.32 |
| ▸ | GCG | P01275 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312897 | 0.90 | CYP2C9 (0.37) | SCDCYP2C9MAPK11MAPK14EGLN1 | |
| SCHEMBL5309204 | 0.87 | SCD (0.37) | SCDCYP2C9MAPK11MAPK14EGLN1 | |
| SCHEMBL5306364 | 0.86 | SCD (0.45) | SCDCYP2C9MAPK11MAPK14P2RX7 | |
| SCHEMBL5309486 | 0.85 | MAPK14 (0.41) | SCDMAPK14EGLN1 | |
| SCHEMBL5306365 | 0.81 | SCD (0.40) | SCDCYP2C9MAPK11MAPK14EGLN1 | |
| SCHEMBL5313381 | 0.80 | SCD (0.41) | SCDCYP2C9MAPK11MAPK14EGLN1 | |
| SCHEMBL5310026 | 0.80 | MAPK8 (0.36) | SCDCYP2C9MAPK11MAPK14EGLN1 | |
| SCHEMBL5309299 | 0.76 | SCD (0.46) | SCDCYP2C9MAPK11MAPK14EGLN1 | |
| SCHEMBL5310725 | 0.76 | SCD (0.41) | SCDCYP2C9MAPK11MAPK14KMT2A | |
| SCHEMBL5309398 | 0.73 | SCD (0.49) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |