Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.36 |
| ▸ | MPL | P40238 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310683 | 0.91 | SCD (0.42) | SCDEGLN1MPLRORCKDM4E | |
| SCHEMBL5330801 | 0.86 | SCD (0.46) | SCD | |
| SCHEMBL5309303 | 0.85 | SCD (0.44) | SCDCYP2C9MAPK11MAPK14MLYCD | |
| SCHEMBL5313381 | 0.83 | SCD (0.41) | SCDCYP2C9MAPK11MAPK14EGLN1 | |
| SCHEMBL5309833 | 0.80 | SCD (0.53) | SCD | |
| SCHEMBL5312639 | 0.80 | SCD (0.38) | SCDCYP2C9MAPK11MAPK14EGLN1 | |
| SCHEMBL5309660 | 0.78 | SCD (0.56) | SCDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL5309157 | 0.77 | SCD (0.55) | SCD | |
| SCHEMBL5307536 | 0.77 | SCD (0.49) | SCD | |
| SCHEMBL5309649 | 0.77 | SCD (0.57) | SCDEGLN1KDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |