Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 10/20 | 0.35 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312639 | 0.90 | SCD (0.38) | SCDP2RX7CYP2C9MAPK11MAPK14 | |
| SCHEMBL5313384 | 0.86 | SCD (0.40) | SCDP2RX7CRACR2ACYP2C9MAPK11 | |
| SCHEMBL5312062 | 0.83 | SCD (0.49) | SCDNPC1ALDH1A1LMNAMAPT | |
| SCHEMBL5310026 | 0.83 | MAPK8 (0.36) | SCDP2RX7CYP2C9MAPK11MAPK14 | |
| SCHEMBL5309299 | 0.83 | SCD (0.46) | SCDP2RX7CRACR2ACYP2C9MAPK11 | |
| SCHEMBL5309201 | 0.80 | SCD (0.39) | SCDP2RX7CYP2C9MAPK11MAPK14 | |
| SCHEMBL5310356 | 0.80 | SMN1; SMN2 (0.44) | SCN9ANPC1ALDH1A1TSHRRAB9A | |
| SCHEMBL5312064 | 0.79 | SCD (0.43) | SCDP2RX7CRACR2A | |
| SCHEMBL5309833 | 0.77 | SCD (0.53) | SCD | |
| SCHEMBL5310683 | 0.77 | SCD (0.42) | SCDCRACR2AEGLN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |