Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309978 | 1.00 | THRA (0.39) | THRATHRBMAPTPOLBALDH1A1 | |
| SCHEMBL14541043 | 0.90 | THRA (0.39) | THRATHRBMAPTPOLBALDH1A1 | |
| SCHEMBL14540667 | 0.90 | THRA (0.40) | THRATHRBKDM4AMAOBPDCD1 | |
| SCHEMBL14540666 | 0.85 | THRA (0.37) | THRATHRBMAPTPOLBALDH1A1 | |
| SCHEMBL14541041 | 0.84 | THRA (0.38) | THRATHRBMAPTPOLBALDH1A1 | |
| SCHEMBL14540986 | 0.84 | THRA (0.34) | THRATHRBMAPTPOLBALDH1A1 | |
| SCHEMBL5314974 | 0.84 | THRA (0.41) | THRATHRBMAPTALDH1A1PDCD1 | |
| SCHEMBL5359578 | 0.84 | THRA (0.41) | THRATHRBMAPTALDH1A1PDCD1 | |
| SCHEMBL14541012 | 0.83 | THRA (0.41) | THRATHRBMAPTALDH1A1KDM4A | |
| SCHEMBL14540614 | 0.80 | THRA (0.38) | THRATHRBALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039125-A2 | AN OPTICALLY ACTIVE THYROID RECEPTOR AGONIST AND OPTICALLY ACTIVE KEY INTERMEDIATES IN ITS PRODUCTION | KARO BIO AB (SE) | 2007-04-12 | — | — | WO | disclosed |