Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 2/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312641 | 0.76 | NISCH (0.41) | ALDH1A1MEN1KMT2APDE3BPDE3A | |
| SCHEMBL5960705 | 0.73 | TDP1 (0.47) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL3790681 | 0.73 | DYRK1A (0.53) | GSK3BCLK1CDK5CDK5R1ALDH1A1 | |
| SCHEMBL3789449 | 0.72 | MAP2K3 (0.44) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL9110917 | 0.72 | CLK1 (0.37) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL11236516 | 0.71 | MAP4K4 (0.51) | GSK3BCLK1CDK5CDK5R1ALDH1A1 | |
| SCHEMBL11364760 | 0.71 | ADRA2A (0.38) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL11366986 | 0.71 | ADRA2A (0.38) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL11370414 | 0.71 | ADRA2A (0.38) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL4858552 | 0.71 | KMT2A (0.48) | GSK3BALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045096-A1 | OLIGOHETEROAROMATIC LUMINISCENT ASSEMBLIES AS HIGH-AFFINITY DNA SEQUENCE-DIRECTED LIGANDS | UNIVERSITY OF SASKATCHEWAN (CA) | 2007-04-26 | — | — | WO | disclosed |
| EP-0556393-B1 | FUSED PYRAZINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 2000-07-26 | — | — | EP | disclosed |
| US-5283244-A | Anticonvulsants, nervous system disorders | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1994-02-01 | — | — | US | disclosed |
| EP-0556393-A1 | FUSED PYRAZINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-08-25 | — | — | EP | disclosed |