Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.81 |
| ▸ | HPGD | P15428 | 11/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.79 |
| ▸ | MAPT | P10636 | 4/20 | 0.79 |
| ▸ | MEN1 | O00255 | 4/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.79 |
| ▸ | HTT | P42858 | 2/20 | 0.79 |
| ▸ | RAB9A | P51151 | 1/20 | 0.79 |
| ▸ | POLB | P06746 | 3/20 | 0.75 |
| ▸ | LMNA | P02545 | 3/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | GLA | P06280 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17774416 | 0.89 | KDM4E (0.68) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL17774411 | 0.88 | KDM4E (0.69) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL16410894 | 0.82 | ALDH1A1 (0.74) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL17774414 | 0.81 | KDM4E (0.67) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL16410877 | 0.78 | MAPT (0.65) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL16410991 | 0.76 | KDM4E (0.84) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL17774410 | 0.76 | KDM4E (0.70) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL7363397 | 0.73 | ERAP1 (0.69) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL16410895 | 0.72 | KDM4E (0.85) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL17774444 | 0.72 | ALDH1A1 (0.57) | KDM4EHPGDALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |