Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.68 |
| ▸ | HPGD | P15428 | 9/20 | 0.68 |
| ▸ | GLA | P06280 | 5/20 | 0.68 |
| ▸ | GAA | P10253 | 5/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KLK7 | P49862 | 1/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | RCE1 | Q9Y256 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4713197 | 0.81 | KDM4E (1.00) | ERAP1KDM4EALDH1A1HPGDGLA | |
| SCHEMBL1448400 | 0.79 | ERAP1 (0.69) | ERAP1KDM4EALDH1A1HPGDGLA | |
| SCHEMBL12325873 | 0.78 | KDM4E (0.98) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL26804638 | 0.73 | KDM4E (0.76) | ERAP1KDM4EALDH1A1HPGDGLA | |
| SCHEMBL5309692 | 0.73 | KDM4E (0.81) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL30776767 | 0.72 | MAPT (0.57) | ERAP1KDM4EALDH1A1HPGDGLA | |
| SCHEMBL16658644 | 0.72 | ALDH1A1 (0.70) | ERAP1KDM4EALDH1A1HPGDGLA | |
| Hydrochloric Acid SCHEMBL4204107 | 0.71 | CRHBP (0.52) | ERAP1KDM4EALDH1A1HPGDGLA | |
| SCHEMBL30022407 | 0.71 | MAPT (0.59) | ERAP1KDM4EALDH1A1HPGDGLA | |
| SCHEMBL16658645 | 0.70 | KDM4E (0.68) | ERAP1KDM4EALDH1A1HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888052-A4 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORP (US) | 2002-05-22 | — | — | EP | disclosed |
| EP-0888052-A1 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORPORATION (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034482-A1 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORP. (US) | 1997-09-25 | — | — | WO | disclosed |