Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309214 | 0.86 | SCD (0.49) | ALDH1A1LMNAMAPTSMN1; SMN2NAAA | |
| SCHEMBL5309801 | 0.85 | LMNA (0.41) | ALDH1A1LMNAMAPTSMN1; SMN2NAAA | |
| SCHEMBL5314476 | 0.85 | EGLN1 (0.39) | NAAASCD | |
| SCHEMBL5315101 | 0.85 | SCD (0.54) | NAAASCD | |
| SCHEMBL5306119 | 0.85 | EGLN1 (0.42) | ALDH1A1SMN1; SMN2HPGDHTTPOLB | |
| SCHEMBL5315083 | 0.84 | SCD (0.54) | SCD | |
| SCHEMBL5309739 | 0.83 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTGSK3BGAA | |
| SCHEMBL5306725 | 0.83 | SCD (0.44) | ALDH1A1LMNAMAPTSMN1; SMN2SCD | |
| SCHEMBL5309157 | 0.81 | SCD (0.55) | SCD | |
| SCHEMBL5307327 | 0.80 | SCD (0.34) | ALDH1A1LMNAMAPTSMN1; SMN2SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |