SCHEMBL5310018

SCHEMBL5310018

O=C(Nc1cccnn1)c1ccc(N2C=CCN(C(=O)c3ccccc3C(F)(F)F)C2)nc1

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SCD O00767 10/20 0.45
DCTPP1 Q9H773 1/20 0.36
GLS O94925 1/20 0.36
MGLL Q99685 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5309113 0.91 SCD (0.47) SCDMGLL
SCHEMBL5306277 0.86 FAAH (0.37) SCD
SCHEMBL5315061 0.85 SCD (0.45) SCDMGLL
SCHEMBL5307322 0.85 SCD (0.54) SCDMGLL
SCHEMBL5306881 0.84 SCD (0.51) SCD
SCHEMBL5309408 0.84 SCD (0.47) SCD
SCHEMBL5309749 0.83 SCD (0.41) SCDGLS
SCHEMBL5310015 0.83 SCD (0.51) SCDDCTPP1
SCHEMBL5308879 0.82 SCD (0.56) SCDDCTPP1
SCHEMBL5307496 0.82 SCD (0.50) SCDMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007046867-A2 PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2007-04-26 WO disclosed