Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.37 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310018 | 0.86 | SCD (0.45) | SCD | |
| SCHEMBL5312568 | 0.85 | FAAH (0.37) | FAAHCRACR2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5306274 | 0.84 | FAAH (0.42) | FAAHKDM4ESCDHDAC2 | |
| SCHEMBL5312567 | 0.80 | FAAH (0.37) | FAAHCRACR2AKDM4EALDH1A1SCD | |
| SCHEMBL5309807 | 0.78 | NPC1 (0.39) | CRACR2ASMN1; SMN2SCDGLAHTT | |
| SCHEMBL5311767 | 0.77 | SMN1; SMN2 (0.45) | CRACR2AALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL5309113 | 0.77 | SCD (0.47) | SCDKMT2A | |
| SCHEMBL5312273 | 0.75 | KCNQ3 (0.44) | KDM4EALDH1A1SMN1; SMN2SCDHTT | |
| SCHEMBL5309408 | 0.74 | SCD (0.47) | CRACR2ASCDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5307080 | 0.73 | SCD (0.40) | KDM4EALDH1A1SCDHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |