Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KDM5A | P29375 | 1/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.51 |
| ▸ | TUBB | P07437 | 2/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29964159 | 0.88 | PKM (0.62) | PKMKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL28012245 | 0.84 | PARP1 (0.56) | PKMKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL6373947 | 0.81 | PKM (0.62) | PKMKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL7441265 | 0.81 | PKM (0.62) | PKMKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL6373754 | 0.81 | PKM (0.62) | PKMKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL21467158 | 0.79 | PKM (0.59) | PKMKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL6373949 | 0.79 | SMN1; SMN2 (0.69) | PKMKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL3423481 | 0.78 | KDM4E (0.59) | KDM4EHSD17B10TUBB4ATUBBTUBA3C | |
| SCHEMBL22275743 | 0.78 | PKM (0.57) | PKMKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL6373903 | 0.78 | PKM (0.57) | PKMKDM4EHPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007042669-A2 | DERIVATIVES OF 4-AMINO-QUINAZOLINE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFIS-AVENTIS (FR) | 2007-04-19 | — | — | WO | disclosed |
| WO-2007042669-A2 | DERIVATIVES OF 4-AMINO-QUINAZOLINE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFIS-AVENTIS (FR) | 2007-04-19 | — | — | WO | disclosed |