Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.65 |
| ▸ | MAOB | P27338 | 4/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.65 |
| ▸ | SDHA | P31040 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CALML3 | P27482 | 1/20 | 0.65 |
| ▸ | F10 | P00742 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648919 | 1.00 | MAOA (0.65) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7840324 | 0.91 | MAOA (0.63) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7840323 | 0.91 | MAOA (0.63) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7831540 | 0.89 | MAOA (0.67) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7831535 | 0.89 | MAOA (0.67) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL4017727 | 0.89 | MAOA (0.66) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7842942 | 0.88 | MAOA (0.65) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3755880 | 0.88 | MAOA (0.65) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7842939 | 0.88 | MAOA (0.65) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3754635 | 0.88 | MAOA (0.65) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007024744-A2 | HETEROCYCLIC CARBOXAMIDE COMPOUNDS AS STEROID NUCLEAR RECEPTOR LIGANDS | EXELIXIS, INC. (US) | 2007-03-01 | — | — | WO | claimed |
| EP-1844020-B1 | HETEROCYCLIC CARBOXAMIDE COMPOUNDS AS STEROID NUCLEAR RECEPTOR LIGANDS | EXELIXIS INC (US) | 2017-09-06 | — | — | EP | disclosed |
| EP-1034175-A1 | SUBSTITUTED PHENYLOXAZOLIDINONES AND THEIR USE AS ANTIBIOTICS | AstraZeneca UK Limited (GB) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999028317-A1 | SUBSTITUTED PHENYLOXAZOLIDINONES AND THEIR USE AS ANTIBIOTICS | ASTRAZENECA UK LIMITED (GB) | 1999-06-10 | — | — | WO | disclosed |