Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | HTT | P42858 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.79 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.79 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | CRHBP | P24387 | 1/20 | 0.63 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312871 | 0.77 | KMT2A (1.00) | ALDH1A1KMT2ALMNAHTTMEN1 | |
| SCHEMBL23183510 | 0.74 | TSHR (0.80) | ALDH1A1KMT2ALMNAHTTMEN1 | |
| SCHEMBL14110759 | 0.74 | TSHR (1.00) | ALDH1A1KMT2ALMNAHTTMEN1 | |
| SCHEMBL12818167 | 0.68 | ALDH1A1 (0.78) | ALDH1A1KMT2ALMNAHTTMEN1 | |
| SCHEMBL20340021 | 0.68 | ALDH1A1 (0.65) | ALDH1A1KMT2ALMNAHTTMEN1 | |
| SCHEMBL30761215 | 0.67 | KMT2A (0.59) | ALDH1A1KMT2ALMNAHTTMEN1 | |
| SCHEMBL20339992 | 0.67 | KMT2A (0.59) | ALDH1A1KMT2ALMNAHTTMEN1 | |
| SCHEMBL13652655 | 0.67 | MAPT (0.82) | ALDH1A1KMT2ALMNAHTTMEN1 | |
| SCHEMBL6321405 | 0.66 | MAPT (0.62) | ALDH1A1SMN1; SMN2HPGDKDM4EHSD17B10 | |
| SCHEMBL24088076 | 0.65 | LMNA (0.55) | ALDH1A1KMT2ALMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |