Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | CASP3 | P42574 | 4/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.51 |
| ▸ | SCD | O00767 | 3/20 | 0.51 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4243614 | 0.79 | CNR1 (0.62) | CNR1ALDH1A1NPC1RAB9APKM | |
| SCHEMBL14808194 | 0.77 | CNR1 (1.00) | CNR1ALDH1A1NPC1RAB9APKM | |
| SCHEMBL4243611 | 0.77 | CNR1 (0.60) | CNR1ALDH1A1NPC1RAB9APKM | |
| SCHEMBL23607124 | 0.77 | CNR1 (0.71) | CNR1ALDH1A1NPC1RAB9APKM | |
| SCHEMBL30553297 | 0.76 | RAB9A (0.70) | CNR1ALDH1A1NPC1RAB9APKM | |
| SCHEMBL4918642 | 0.76 | HTT (0.76) | CNR1ALDH1A1NPC1RAB9APKM | |
| SCHEMBL4912955 | 0.76 | DHODH (0.76) | CNR1ALDH1A1NPC1RAB9APKM | |
| SCHEMBL2242970 | 0.76 | CNR1 (0.69) | CNR1ALDH1A1NPC1RAB9APKM | |
| SCHEMBL6688359 | 0.75 | CNR1 (0.68) | CNR1ALDH1A1NPC1RAB9APKM | |
| SCHEMBL27929350 | 0.75 | CNR1 (0.68) | CNR1ALDH1A1NPC1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863771-A2 | BENZAZOLE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE AS B-SECRETASE INHIBITORS | Transtech Pharma, Inc. (US) | 2007-12-12 | — | — | EP | claimed |
| WO-2006099379-A2 | BENZAZOLE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE AS B-SECRETASE INHIBITORS | TRANSTECH PHARMA, INC. (US) | 2006-09-21 | — | — | WO | claimed |