Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | PNLIP | P16233 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216339 | 0.93 | GAA (0.63) | GAAPNLIPALDH1A1L3MBTL1TDP1 | |
| SCHEMBL5216347 | 0.82 | ALDH1A1 (0.68) | GAAPNLIPALDH1A1TDP1POLB | |
| SCHEMBL8730078 | 0.79 | TDP1 (0.65) | GAAALDH1A1L3MBTL1TDP1MEN1 | |
| SCHEMBL2781160 | 0.78 | GAA (0.67) | GAAALDH1A1L3MBTL1TDP1MEN1 | |
| SCHEMBL5213935 | 0.77 | GAA (0.62) | GAAALDH1A1L3MBTL1TDP1MEN1 | |
| SCHEMBL6455377 | 0.77 | RAB9A (0.74) | GAAALDH1A1L3MBTL1TDP1MEN1 | |
| SCHEMBL8730084 | 0.76 | TDP1 (0.70) | GAAALDH1A1L3MBTL1TDP1MEN1 | |
| SCHEMBL26054536 | 0.75 | GAA (0.60) | GAAALDH1A1L3MBTL1TDP1MEN1 | |
| SCHEMBL6063263 | 0.75 | CNR1 (0.58) | ALDH1A1KMT2AKDM4E | |
| SCHEMBL4087178 | 0.75 | MAPK8 (0.69) | KMT2AMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |