Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29207125 | 0.86 | TSHR (0.33) | ALDH1A1 | |
| SCHEMBL14403101 | 0.86 | THRB (0.36) | THRB | |
| SCHEMBL28559553 | 0.82 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL8750324 | 0.81 | THRB (0.39) | THRB | |
| SCHEMBL29396142 | 0.81 | MEN1 (0.35) | THRB | |
| SCHEMBL5310350 | 0.81 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL1982323 | 0.80 | TSHR (0.44) | THRBALDH1A1 | |
| SCHEMBL10339404 | 0.78 | USP2 (0.47) | THRBALDH1A1 | |
| SCHEMBL17471828 | 0.78 | SMPD1 (0.39) | — | |
| SCHEMBL738846 | 0.77 | TSHR (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411053-B1 | METHOD FOR OBTAINING DERIVATIVES OF (PYRIDIL SUBSTITUTED)METHYL|THIO|BENZIMIDAZOL | ESTEVE QUIMICA SA (ES) | 2007-05-30 | — | — | EP | disclosed |
| EP-1411053-A1 | METHOD FOR OBTAINING DERIVATIVES OF (PYRIDIL SUBSTITUTED)METHYL]THIO]BENZIMIDAZOL | ESTEVE QUIMICA, S.A. (ES) | 2004-04-21 | — | — | EP | disclosed |
| US-6723852-B2 | REACTING AN N-OXIDE OF METHYLPYRIDINE COMPOUND WITH ANHYDRIDE OF AN ACTIVATED CARBOXYLIC ACID OR WITH ANHYDRIDE OF SULFONIC ACID IN SOLVENT; REACTING INTERMEDIATE WITH DERIVATIVE OF 2-MERCAPTOBENZOMIDAZOL | ESTEVE QUIMICA, S.A. (ES) | 2004-04-20 | — | — | US | disclosed |
| US-20030036656-A1 | Method for obtaining derivatives of [ [(pyridil substituted)methyl]thio]benzomidazol | ESTEVE QUIMICA, S.A. (ES) | 2003-02-20 | — | — | US | disclosed |
| US-5288340-A | Oxidation, coating with heat-hardenable resin | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1994-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030036656-A1 | Method for obtaining derivatives of [ [(pyridil substituted)methyl]thio]benzomidazol | TPMT, CYP2C8, HRH2 | THRB 2500/4885ALDH1A1 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.