Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | LTC4S | Q16873 | 2/20 | 0.47 |
| ▸ | RORC | P51449 | 4/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.46 |
| ▸ | ASPH | Q12797 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.43 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313203 | 0.91 | CNR2 (0.53) | CNR2LTC4SRORCNR1H2NR1H3 | |
| SCHEMBL5307717 | 0.85 | ASPH (0.45) | ASPHP4HTMP4HA1MIFKMO | |
| SCHEMBL5313162 | 0.80 | CNR2 (0.48) | CNR2LTC4SRORCNR1H2NR1H3 | |
| SCHEMBL5315546 | 0.79 | SCD (0.51) | — | |
| SCHEMBL3717986 | 0.77 | GAA (0.56) | CNR2NR1H2NR1H3CTNNB1WNT3A | |
| SCHEMBL31369140 | 0.77 | GAA (0.56) | CNR2NR1H2NR1H3CTNNB1WNT3A | |
| SCHEMBL5315830 | 0.75 | ASPH (0.48) | ASPHP4HTMKMO | |
| SCHEMBL71034 | 0.75 | HIF1A (0.55) | P4HTMP4HA1MIF | |
| SCHEMBL29929320 | 0.75 | HIF1A (0.55) | P4HTMP4HA1MIF | |
| SCHEMBL5131139 | 0.74 | KMT2A (0.53) | ASPHP4HTMP4HA1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044085-A2 | HETEROARYL COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-19 | — | — | WO | disclosed |