Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.43 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 7/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313203 | 0.89 | CNR2 (0.53) | CNR2LTC4SASPHKMORORC | |
| SCHEMBL5307870 | 0.86 | ASPH (0.43) | ASPHKMOSCD | |
| SCHEMBL5310783 | 0.81 | SCD (0.46) | CNR2SCD | |
| SCHEMBL5312220 | 0.80 | SCD (0.47) | SCD | |
| SCHEMBL5310364 | 0.80 | CNR2 (0.47) | CNR2LTC4SASPHKMORORC | |
| SCHEMBL5313732 | 0.79 | NPC1 (0.46) | GAALMNASCD | |
| SCHEMBL5307859 | 0.74 | CNR2 (0.42) | CNR2LTC4SKMORORCCTNNB1 | |
| SCHEMBL5307724 | 0.74 | USP30 (0.47) | CNR2GAALMNASCD | |
| SCHEMBL5376686 | 0.74 | NPC1 (0.39) | ASPHKMOSCD | |
| SCHEMBL5313199 | 0.74 | HPGDS (0.52) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044085-A2 | HETEROARYL COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-19 | — | — | WO | disclosed |