Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332877 | 0.86 | — | — | |
| SCHEMBL1118323 | 0.81 | RPS6KA3 (0.38) | RPS6KA3KDM4EBRD4ALDH1A1BRPF1 | |
| SCHEMBL50474 | 0.68 | RPS6KA3 (0.39) | RPS6KA3KDM4EBRD4ALDH1A1BRPF1 | |
| SCHEMBL3945086 | 0.62 | RPS6KA3 (0.40) | RPS6KA3KDM4EBRD4ALDH1A1BRPF1 | |
| SCHEMBL841837 | 0.61 | RPS6KA3 (0.41) | RPS6KA3KDM4EBRD4ALDH1A1BRPF1 | |
| SCHEMBL5329442 | 0.60 | SRD5A2 (0.39) | RPS6KA3 | |
| SCHEMBL1978812 | 0.58 | RPS6KA3 (0.85) | RPS6KA3 | |
| SCHEMBL4823385 | 0.58 | RPS6KA3 (0.41) | RPS6KA3 | |
| SCHEMBL4831486 | 0.58 | RPS6KA3 (0.41) | RPS6KA3 | |
| SCHEMBL4829827 | 0.58 | RPS6KA3 (0.41) | RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007033175-A1 | INDOLOBENZAZEPINE HCV NS5B INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-03-22 | — | — | WO | disclosed |