Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6050079 | 0.83 | EPHX2 (0.41) | ALDH1A1KMT2AKLK7ATMMEN1 | |
| SCHEMBL7449462 | 0.83 | KMT2A (0.40) | ALDH1A1TDP1KMT2ACYP1A2MGAM | |
| SCHEMBL3632776 | 0.75 | ALDH1A1 (0.36) | ALDH1A1TDP1KMT2AL3MBTL1MEN1 | |
| SCHEMBL2648207 | 0.75 | MEN1 (0.51) | ALDH1A1TDP1USP2ALOX15KMT2A | |
| SCHEMBL7052823 | 0.75 | KMT2A (0.38) | ALDH1A1TDP1USP2ALOX15KMT2A | |
| SCHEMBL1172293 | 0.74 | MEN1 (0.54) | ALDH1A1TDP1USP2ALOX15KMT2A | |
| SCHEMBL18311726 | 0.74 | MEN1 (0.54) | ALDH1A1TDP1USP2ALOX15KMT2A | |
| SCHEMBL9744436 | 0.74 | MEN1 (0.54) | ALDH1A1TDP1USP2ALOX15KMT2A | |
| SCHEMBL31323929 | 0.74 | MEN1 (0.54) | ALDH1A1TDP1USP2ALOX15KMT2A | |
| SCHEMBL234450 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KMT2AL3MBTL1ATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833806-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | AstraZeneca AB (SE) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006064189-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | WO | disclosed |