Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310378 | 0.83 | ALDH1A1 (0.41) | KMT2APOLBMGAMGAASI | |
| SCHEMBL3549456 | 0.82 | EPHX2 (0.38) | POLBMGAMGAASIMGAM2 | |
| SCHEMBL2911152 | 0.79 | POLB (0.36) | KMT2APOLBMGAMGAASI | |
| SCHEMBL2915904 | 0.78 | POLB (0.36) | KMT2APOLBMGAMGAASI | |
| SCHEMBL2915475 | 0.78 | POLB (0.36) | KMT2APOLBMGAMGAASI | |
| SCHEMBL2917399 | 0.76 | SMN1; SMN2 (0.35) | KMT2APOLBMGAMGAASI | |
| SCHEMBL2910368 | 0.75 | POLB (0.37) | KMT2APOLBMGAMGAASI | |
| SCHEMBL2916000 | 0.74 | SLC6A12 (0.36) | POLBALDH1A1TDP1 | |
| SCHEMBL15653541 | 0.74 | MGAM (0.46) | KMT2APOLBMGAMGAASI | |
| SCHEMBL1439129 | 0.74 | TDP1 (0.48) | KMT2APOLBMGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087888-A1 | PYRAZOLOPYRIMIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | SK CHEMICALS CO., LTD. (KR) | 2001-11-22 | — | — | WO | disclosed |