Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 5/20 | 0.36 |
| ▸ | AR | P10275 | 5/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.34 |
| ▸ | ESR1 | P03372 | 4/20 | 0.34 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5494151 | 0.80 | CYP19A1 (0.48) | NR1I3SHBGCYP19A1CYP17A1 | |
| SCHEMBL16011818 | 0.79 | MAPT (0.43) | ALDH1A1NR1I3MAPTKDM4ESHBG | |
| SCHEMBL16011817 | 0.79 | MAPT (0.43) | ALDH1A1NR1I3MAPTKDM4ESHBG | |
| SCHEMBL5309770 | 0.77 | AR (0.32) | MAPTSHBGARESR2ESR1 | |
| SCHEMBL5311136 | 0.75 | CYP17A1 (0.38) | ALDH1A1SHBGARESR2ESR1 | |
| SCHEMBL5572192 | 0.74 | L3MBTL1 (0.38) | ALDH1A1SHBGARESR2ESR1 | |
| SCHEMBL5574814 | 0.74 | L3MBTL1 (0.38) | ALDH1A1SHBGARESR2ESR1 | |
| SCHEMBL941737 | 0.73 | SHBG (0.63) | SHBGARESR2ESR1SERPINA6 | |
| SCHEMBL1649014 | 0.73 | SHBG (0.63) | SHBGARESR2ESR1SERPINA6 | |
| SCHEMBL5308289 | 0.73 | SHBG (0.63) | SHBGARESR2ESR1SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007030124-A2 | TREATMENT SCREENING METHODS | HOLLIS-EDEN PHARMACEUTICALS, INC (US) | 2007-03-15 | — | — | WO | disclosed |