Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 13/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | CCKBR | P32239 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020897 | 0.79 | HDAC3 (0.61) | TRPV1MGAMHDAC3HDAC1HDAC2 | |
| SCHEMBL12505087 | 0.79 | TRPV1 (0.51) | TRPV1MGAMHDAC3HDAC1HDAC2 | |
| SCHEMBL11416534 | 0.77 | NAAA (0.55) | HDAC3HDAC1HDAC2 | |
| SCHEMBL10242977 | 0.75 | HDAC3 (0.61) | TRPV1MGAMHDAC3HDAC1HDAC2 | |
| SCHEMBL2625196 | 0.75 | MGAM (0.65) | TRPV1MGAM | |
| SCHEMBL531058 | 0.74 | NAAA (0.50) | TRPV1HDAC3HDAC1HDAC2 | |
| SCHEMBL12505086 | 0.74 | TRPV1 (0.43) | TRPV1HDAC3HDAC1HDAC2 | |
| SCHEMBL13610181 | 0.73 | LMNA (0.55) | TRPV1MGAM | |
| SCHEMBL27391699 | 0.73 | LMNA (0.55) | TRPV1MGAM | |
| SCHEMBL9360308 | 0.73 | MGAM (0.58) | TRPV1MGAMHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2597955-A1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | OncoTherapy Science, Inc. (JP) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012016082-A1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE, INC. (JP) | 2012-02-02 | — | — | WO | disclosed |