⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315490 | 0.78 | CA2 (0.35) | — | |
| SCHEMBL12018615 | 0.74 | — | — | |
| SCHEMBL23449937 | 0.66 | — | — | |
| SCHEMBL5474939 | 0.64 | LAP3 (0.30) | — | |
| SCHEMBL1628667 | 0.63 | — | — | |
| SCHEMBL8371324 | 0.63 | — | — | |
| SCHEMBL20633922 | 0.60 | CA2 (0.37) | — | |
| SCHEMBL12018477 | 0.59 | — | — | |
| SCHEMBL10713761 | 0.59 | — | — | |
| SCHEMBL10497030 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629617-B2 | Heteroatom-bearing ligands and metal complexes thereof | BRACCO INT BV (NL) | 2007-09-26 | — | — | EP | disclosed |
| US-5997843-A | TECHNETIUM-99M | AMERSHAM INTERNATIONAL PLC (GB) | 1999-12-07 | — | — | US | disclosed |
| EP-0629617-B1 | Heteroatom-bearing ligands and metal complexes thereof | BRACCO INT BV (NL) | 1998-04-29 | — | — | EP | disclosed |
| US-5741912-A | DIAGNOSIS, THERAPY | BRACCO INTERNATIONAL B.V. | 1998-04-21 | — | — | US | disclosed |
| US-5665329-A | Heteroatom-bearing ligands and metal complexes thereof | BRACCO INTERNATIONAL B.V. | 1997-09-09 | — | — | US | disclosed |
| US-5656254-A | Polyaza heteroatom-bearing ligands and metal complexes thereof for imaging or radiotherapy | BRACCO INTERNATIONAL B.V. | 1997-08-12 | — | — | US | disclosed |
| US-5627286-A | Heteroatom-bearing ligands and metal complexes thereof | BRACCO INTERNATIONAL B.V. | 1997-05-06 | — | — | US | disclosed |
| US-5608110-A | Heteroatom-bearing ligands and metal complexes thereof | BRACCO INTERNATIONAL B.V. | 1997-03-04 | — | — | US | disclosed |
| EP-0712315-A1 | RADIOMETAL COMPLEXES THAT LOCALISE IN HYPOXIC TISSUE | AMERSHAM INTERNATIONAL plc (GB) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995004552-A2 | RADIOMETAL COMPLEXES THAT LOCALISE IN HYPOXIC TISSUE | AMERSHAM INTERNATIONAL PLC (GB) | 1995-02-16 | — | — | WO | disclosed |
| EP-0629617-A1 | Heteroatom-bearing ligands and metal complexes thereof | BRACCO International B.V. (NL) | 1994-12-21 | — | — | EP | disclosed |
| EP-0123504-B1 | COMPLEXES OF TECHNETIUM-99M WITH ALKYLENE AMINE OXIMES | AMERSHAM INTERNATIONAL plc (GB) | 1989-09-20 | — | — | EP | disclosed |
| EP-0123504-A2 | Complexes of technetium-99m with alkylene amine oximes | AMERSHAM INTERNATIONAL plc (GB) | 1984-10-31 | — | — | EP | disclosed |