Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11781117 | 0.98 | HTT (0.50) | KDM4EPKMHTTKMT2ALMNA | |
| SCHEMBL9346814 | 0.98 | KDM4E (0.53) | KDM4EPKMHTTKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL11779650 | 0.96 | KDM4E (0.52) | KDM4EPKMHTTKMT2ALMNA | |
| SCHEMBL2466537 | 0.92 | ACHE (0.47) | KDM4EPKMHTTKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL12813545 | 0.91 | KMT2A (0.49) | KDM4EPKMHTTKMT2ALMNA | |
| SCHEMBL9278692 | 0.84 | PABPC1 (0.49) | KDM4EPKMHTTKMT2ALMNA | |
| SCHEMBL8851140 | 0.84 | ACHE (0.41) | KDM4EPKMHTTKMT2ALMNA | |
| SCHEMBL4214710 | 0.83 | ACHE (0.47) | KMT2AMEN1HRH3ACHE | |
| Formic Acid SCHEMBL5085570 | 0.83 | KMT2A (0.44) | KDM4EPKMHTTKMT2AHPGD | |
| SCHEMBL13011025 | 0.82 | CYP2D6 (0.59) | KDM4EPKMHTTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964693-A1 | STORAGE STABLE FOAMABLE COMPOSITIONS CONTAINING 1,1,1,4,4,4-HEXAFLUORO-2-BUTENE | Honeywell International Inc. (US) | 2016-01-13 | — | — | EP | disclosed |
| WO-2014137969-A1 | STORAGE STABLE FOAMABLE COMPOSITIONS CONTAINING 1,1,1,4,4,4-HEXAFLUORO-2-BUTENE | HONEYWELL INTERNATIONAL INC. (US) | 2014-09-12 | — | — | WO | disclosed |
| WO-2012015887-A2 | FOAMS AND ARTICLES MADE FROM FOAMS CONTAINING 1-CHLORO-3,3,3-TRIFLUOROPROPENE (HCFO-1233ZD) | HONEYWELL INTERNATIONAL INC. (US) | 2012-02-02 | — | — | WO | disclosed |
| US-20070149560-A1 | Novel fused triazolones and the uses thereof | ASTRAZENECA AB (SE) | 2007-06-28 | — | — | US | disclosed |
| US-20070149560-A1 | Novel fused triazolones and the uses thereof | ASTRAZENECA AB (SE) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149560-A1 | Novel fused triazolones and the uses thereof | TP53, BRCA1, KLK3 | KDM4E 3368/4885PKM 1374/4885HTT 2807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.