Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.72 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31396266 | 0.89 | HDAC1 (0.58) | HTTHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL619633 | 0.84 | HTT (1.00) | HTTHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL30270528 | 0.84 | HTT (1.00) | HTTHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL3324598 | 0.83 | LMNA (0.76) | HTTHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL1238568 | 0.76 | HTT (0.56) | HTTHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL5507140 | 0.76 | HDAC1 (0.57) | HTTHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL8853550 | 0.76 | HDAC1 (0.57) | HDAC1HDAC8HDAC6LMNATP53 | |
| SCHEMBL5638460 | 0.76 | KMT2A (0.62) | HTTHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL10352557 | 0.76 | LMNA (0.57) | HTTHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL5745653 | 0.76 | HDAC1 (0.57) | HTTHDAC1HDAC8HDAC6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007016610-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-02-08 | — | — | WO | disclosed |
| WO-2007016610-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-02-08 | — | — | WO | disclosed |