Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | VHL | P40337 | 1/20 | 0.54 |
| ▸ | ELOC | Q15369 | 1/20 | 0.54 |
| ▸ | ELOB | Q15370 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 2/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629681 | 0.90 | KMT2A (0.49) | HDAC1HDAC8HDAC6KMT2AVHL | |
| SCHEMBL7454625 | 0.83 | HTT (0.59) | KMT2ATP53AHRCMA1MAPT | |
| SCHEMBL5638460 | 0.80 | KMT2A (0.62) | HDAC1HDAC8HDAC6KMT2ATP53 | |
| SCHEMBL5507140 | 0.80 | HDAC1 (0.57) | HDAC1HDAC8HDAC6KMT2ATP53 | |
| SCHEMBL5255291 | 0.78 | TP53 (0.60) | HDAC1HDAC8HDAC6KMT2ATP53 | |
| SCHEMBL3328663 | 0.78 | HDAC1 (0.55) | HDAC1HDAC8HDAC6KMT2AVHL | |
| SCHEMBL5745653 | 0.76 | HDAC1 (0.57) | HDAC1HDAC8HDAC6KMT2ATP53 | |
| SCHEMBL5311151 | 0.76 | HTT (0.73) | HDAC1HDAC8HDAC6KMT2ATP53 | |
| SCHEMBL10075537 | 0.76 | HDAC1 (0.53) | HDAC1HDAC8HDAC6KMT2ATP53 | |
| SCHEMBL8853694 | 0.76 | MAOA (0.57) | HDAC1HDAC8HDAC6KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657407-B1 | Process for the preparation of 3-fluoro-4,6-dichlorotoluene | BAYER AG (DE) | 1997-12-10 | — | — | EP | disclosed |
| US-5475164-A | Process for preparing 3-fluoro-4,6-dichlorotoluene | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |
| EP-0657407-A1 | Process for the preparation of 3-fluoro-4,6-dichlorotoluene | BAYER AG (DE) | 1995-06-14 | — | — | EP | disclosed |
| EP-0292824-B1 | PROCESS FOR THE NUCLEAR CHLORINATION OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1990-08-01 | — | — | EP | disclosed |
| US-4851596-A | Process for nucleus-chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-25 | — | — | US | disclosed |
| EP-0292824-A1 | Process for the nuclear chlorination of aromatic hydrocarbons | BAYER AG (DE) | 1988-11-30 | — | — | EP | disclosed |