Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311431 | 0.86 | HSD11B1 (0.51) | CNR2CNR1HSD11B1HCRTR1HCRTR2 | |
| SCHEMBL5316746 | 0.85 | ITGB1 (0.50) | CNR2CNR1HSD11B1HCRTR1HCRTR2 | |
| SCHEMBL7998357 | 0.77 | POLB (0.54) | HSD11B1ALDH1A1HTTHCRTR1HCRTR2 | |
| SCHEMBL14529760 | 0.76 | HSD11B1 (0.61) | HSD11B1L3MBTL1 | |
| SCHEMBL5315648 | 0.76 | HSD11B1 (0.61) | HSD11B1L3MBTL1 | |
| SCHEMBL6336066 | 0.76 | HSD11B1 (0.60) | HSD11B1ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL3454744 | 0.72 | HSD11B1 (0.69) | CNR2CNR1HSD11B1ALDH1A1MAPT | |
| SCHEMBL14530359 | 0.72 | HSD11B1 (0.52) | HSD11B1MAPTSMN1; SMN2HCRTR1HCRTR2 | |
| SCHEMBL14529612 | 0.72 | HSD11B1 (0.46) | HSD11B1SMN1; SMN2HCRTR1HCRTR2 | |
| SCHEMBL14529916 | 0.72 | HSD11B1 (0.46) | HSD11B1SMN1; SMN2HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057768-A2 | SULFONYL DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-05-24 | — | — | WO | disclosed |