Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 9/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 9/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.50 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311431 | 0.91 | HSD11B1 (0.51) | ITGB1ITGA4HSD11B1ITGB7HCRTR1 | |
| SCHEMBL5311429 | 0.85 | CNR2 (0.51) | HSD11B1HCRTR1HCRTR2CNR1CNR2 | |
| SCHEMBL14530361 | 0.85 | ITGB1 (0.46) | ITGB1ITGA4HSD11B1ITGB7HCRTR1 | |
| SCHEMBL14529760 | 0.85 | HSD11B1 (0.61) | ITGB1ITGA4HSD11B1ITGB7 | |
| SCHEMBL5315648 | 0.85 | HSD11B1 (0.61) | ITGB1ITGA4HSD11B1ITGB7 | |
| SCHEMBL14529609 | 0.84 | HSD11B1 (0.45) | ITGB1ITGA4HSD11B1ITGB7HCRTR1 | |
| SCHEMBL14529605 | 0.83 | ITGB1 (0.53) | ITGB1ITGA4HSD11B1ITGB7 | |
| SCHEMBL14529918 | 0.79 | HCRTR1 (0.43) | ITGB1ITGA4HSD11B1ITGB7HCRTR1 | |
| SCHEMBL12640491 | 0.78 | HCRTR1 (0.57) | ITGB1ITGA4HSD11B1ITGB7HCRTR1 | |
| SCHEMBL14529612 | 0.76 | HSD11B1 (0.46) | ITGB1ITGA4HSD11B1ITGB7HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057768-A2 | SULFONYL DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-05-24 | — | — | WO | disclosed |