Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 7/20 | 1.00 |
| ▸ | CA2 | P00918 | 12/20 | 0.87 |
| ▸ | CA9 | Q16790 | 11/20 | 0.87 |
| ▸ | CA1 | P00915 | 11/20 | 0.87 |
| ▸ | CA12 | O43570 | 7/20 | 0.87 |
| ▸ | CA7 | P43166 | 4/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311444 | 1.00 | PTGS2 (1.00) | PTGS2PTGS1CA2CA9CA1 | |
| SCHEMBL5310957 | 0.93 | PTGS2 (1.00) | PTGS2PTGS1CA2CA9CA1 | |
| SCHEMBL1517598 | 0.93 | PTGS2 (1.00) | PTGS2PTGS1CA2CA9CA1 | |
| SCHEMBL5309673 | 0.83 | PTGS2 (1.00) | PTGS2PTGS1CA2CA9CA1 | |
| SCHEMBL5314091 | 0.83 | CA2 (1.00) | PTGS2PTGS1CA2CA9CA1 | |
| SCHEMBL5312743 | 0.83 | PTGS2 (1.00) | PTGS2PTGS1CA2CA9CA1 | |
| SCHEMBL5311687 | 0.83 | PTGS2 (1.00) | PTGS2PTGS1CA2CA9CA1 | |
| SCHEMBL5314088 | 0.83 | CA2 (1.00) | PTGS2PTGS1CA2CA9CA1 | |
| SCHEMBL5312741 | 0.83 | PTGS2 (1.00) | PTGS2PTGS1CA2CA9CA1 | |
| SCHEMBL18719842 | 0.83 | CA2 (1.00) | PTGS2PTGS1CA2CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799823-B1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | DAIICHI SANKYO CO LTD (JP) | 2007-10-31 | — | — | EP | disclosed |
| EP-0799823-A1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1997-10-08 | — | — | EP | disclosed |