Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312684 | 0.83 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL5314070 | 0.83 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL5314508 | 0.79 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL5309149 | 0.78 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL5309608 | 0.75 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5314063 | 0.75 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL1155193 | 0.75 | PTGS2 (0.42) | PTGS2PTGS1 | |
| SCHEMBL8502465 | 0.75 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL5308875 | 0.75 | CHRNA7 (0.63) | PTGS2PTGS1AOC3 | |
| SCHEMBL5311718 | 0.75 | PTGS2 (0.69) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799823-B1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | DAIICHI SANKYO CO LTD (JP) | 2007-10-31 | — | — | EP | disclosed |
| US-RE39420-E1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | SANKYO COMPANY, LIMITED (JP) | 2006-12-05 | — | — | US | disclosed |
| US-5908858-A | OSTEOPOROSIS; LEUKOTRIENE INHIBITOR | SANKYO COMPANY, LIMITED (JP) | 1999-06-01 | — | — | US | disclosed |
| EP-0799823-A1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1997-10-08 | — | — | EP | disclosed |