Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.74 |
| ▸ | LSS | P48449 | 3/20 | 0.72 |
| ▸ | PKM | P14618 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | F13A1 | P00488 | 1/20 | 0.62 |
| ▸ | TGM2 | P21980 | 1/20 | 0.62 |
| ▸ | TGM1 | P22735 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6179932 | 0.91 | LSS (0.65) | CNR1LSSPKML3MBTL1NPSR1 | |
| SCHEMBL751854 | 0.85 | ALDH1A1 (0.87) | CNR1PKML3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL6981358 | 0.85 | LSS (0.61) | CNR1LSSL3MBTL1ALDH1A1 | |
| SCHEMBL7401658 | 0.84 | LSS (1.00) | CNR1LSSL3MBTL1 | |
| SCHEMBL6980123 | 0.83 | LSS (0.60) | CNR1LSSPKMALDH1A1F13A1 | |
| SCHEMBL7660042 | 0.83 | LSS (0.77) | CNR1LSSL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL7086266 | 0.82 | ALDH1A1 (0.59) | LSSPKMALDH1A1F13A1TGM2 | |
| SCHEMBL751747 | 0.82 | CNR1 (0.69) | CNR1PKML3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL1387276 | 0.82 | LSS (0.94) | CNR1LSSL3MBTL1ALDH1A1 | |
| SCHEMBL5443874 | 0.81 | GPR183 (0.63) | PKMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039578-A1 | IMIDAZOLYL-SUBSTITUTED AZABENZOPHENONE COMPOUNDS | NYCOMED GMBH (DE) | 2007-04-12 | — | — | WO | disclosed |