SCHEMBL531154

SCHEMBL531154

CCCCCCCCCCCC(C(=O)Oc1ccc([N+](=O)[O-])cc1)C(=O)Oc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.65
L3MBTL1 Q9Y468 2/20 0.65
CRHBP P24387 1/20 0.63
CRHR2 Q13324 1/20 0.63
MGLL Q99685 2/20 0.61
BCL9 O00512 1/20 0.56
CTNNB1 P35222 1/20 0.56
GAA P10253 1/20 0.51
HTR2A P28223 1/20 0.46
ALDH1A1 P00352 2/20 0.45
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ACHE P22303 1/20 0.43
SLC6A4 P31645 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11063253 0.89 MGLL (0.61) MAPTL3MBTL1CRHBPCRHR2MGLL
SCHEMBL11064813 0.89 MGLL (0.61) MAPTL3MBTL1CRHBPCRHR2MGLL
SCHEMBL11060689 0.89 MGLL (0.61) MAPTL3MBTL1CRHBPCRHR2MGLL
SCHEMBL7075032 0.88 MGLL (0.60) MAPTL3MBTL1CRHBPCRHR2MGLL
SCHEMBL7073161 0.88 MGLL (0.60) MAPTL3MBTL1CRHBPCRHR2MGLL
SCHEMBL60448 0.88 MGLL (0.60) MAPTL3MBTL1CRHBPCRHR2MGLL
SCHEMBL28063044 0.88 MGLL (0.60) MAPTL3MBTL1CRHBPCRHR2MGLL
SCHEMBL28497167 0.87 MGLL (0.58) MAPTL3MBTL1CRHBPCRHR2MGLL
SCHEMBL29277468 0.86 MGLL (0.57) MAPTL3MBTL1CRHBPCRHR2MGLL
SCHEMBL28120256 0.85 MGLL (0.56) MAPTL3MBTL1CRHBPCRHR2MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1313794-B1 ELASTOMERIC FUNCTIONAL BIODEGRADABLE COPOLYESTER AMIDES AND COPOLYESTER URETHANES CORNELL RES FOUNDATION INC (US) 2006-11-29 EP claimed
US-20040063606-A1 Elastomeric functional biodegradable copolyester amides and copolyester urethanes CORNELL RESEARCH FOUNDATION, INC. 2004-04-01 US claimed
EP-1313794-A2 ELASTOMERIC FUNCTIONAL BIODEGRADABLE COPOLYESTER AMIDES AND COPOLYESTER URETHANES CORNELL RESEARCH FOUNDATION, INC. (US) 2003-05-28 EP claimed
US-6503538-B1 Elastomeric functional biodegradable copolyester amides and copolyester urethanes CORNELL RESEARCH FOUNDATION, INC. 2003-01-07 US claimed
WO-2002018477-A2 ELASTOMERIC FUNCTIONAL BIODEGRADABLE COPOLYESTER AMIDES AND COPOLYESTER URETHANES CORNELL RESEARCH FOUNDATION, INC. (US) 2002-03-07 WO claimed
EP-2413909-B1 MULTIAMINO ACID-BASED POLY (ESTER AMIDE)S UNIV CORNELL (US) 2016-11-30 EP disclosed
US-8993686-B2 Multiamino acid-based poly(ester amide)s CORNELL UNIVERSITY (US) 2015-03-31 US disclosed
US-20120123064-A1 Multiamino Acid-Based Poly(Ester Amide)s CORNELL UNIVERSITY (US) 2012-05-17 US disclosed
EP-2413909-A1 MULTIAMINO ACID-BASED POLY (ESTER AMIDE)S Cornell University (US) 2012-02-08 EP disclosed
WO-2010114601-A1 MULTIAMINO ACID-BASED POLY (ESTER AMIDE)S CORNELL UNIVERSITY (US) 2010-10-07 WO disclosed
US-7408018-B2 Elastomeric functional biodegradable copolyester amides and copolyester urethanes CORNELL RESEARCH FOUNDATION, INC. (US) 2008-08-05 US disclosed
US-7304122-B2 Useful as carriers of drugs or other bioactive substances; polymers can be linked, intermixed, or a combination thereof, to one or more drugs CORNELL RESEARCH FOUNDATION, INC. (US) 2007-12-04 US disclosed
US-20070027293-A1 Elastomeric functional biodegradable copolyester amides and copolyester urethanes CORNELL RESEARCH FOUNDATION, INC. 2007-02-01 US disclosed
EP-1313794-B1 ELASTOMERIC FUNCTIONAL BIODEGRADABLE COPOLYESTER AMIDES AND COPOLYESTER URETHANES CORNELL RES FOUNDATION INC (US) 2006-11-29 EP disclosed
US-20040063606-A1 Elastomeric functional biodegradable copolyester amides and copolyester urethanes CORNELL RESEARCH FOUNDATION, INC. 2004-04-01 US disclosed
EP-1313794-A2 ELASTOMERIC FUNCTIONAL BIODEGRADABLE COPOLYESTER AMIDES AND COPOLYESTER URETHANES CORNELL RESEARCH FOUNDATION, INC. (US) 2003-05-28 EP disclosed
US-6503538-B1 Elastomeric functional biodegradable copolyester amides and copolyester urethanes CORNELL RESEARCH FOUNDATION, INC. 2003-01-07 US disclosed
WO-2002018477-A2 ELASTOMERIC FUNCTIONAL BIODEGRADABLE COPOLYESTER AMIDES AND COPOLYESTER URETHANES CORNELL RESEARCH FOUNDATION, INC. (US) 2002-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063606-A1 Elastomeric functional biodegradable copolyester amides and copolyester urethanes PUF60, UROD, UBE2I MAPT 1304/4885L3MBTL1 2494/4885CRHBP 615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.