Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.60 |
| ▸ | BCL9 | O00512 | 1/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7075032 | 1.00 | MGLL (0.60) | MGLLBCL9CTNNB1MAPTL3MBTL1 | |
| SCHEMBL7073161 | 1.00 | MGLL (0.60) | MGLLBCL9CTNNB1MAPTL3MBTL1 | |
| SCHEMBL28063044 | 1.00 | MGLL (0.60) | MGLLBCL9CTNNB1MAPTL3MBTL1 | |
| SCHEMBL29277468 | 0.99 | MGLL (0.57) | MGLLBCL9CTNNB1MAPTL3MBTL1 | |
| SCHEMBL531154 | 0.88 | MAPT (0.65) | MGLLBCL9CTNNB1MAPTL3MBTL1 | |
| SCHEMBL11063253 | 0.88 | MGLL (0.61) | MGLLBCL9CTNNB1MAPTL3MBTL1 | |
| SCHEMBL11064813 | 0.88 | MGLL (0.61) | MGLLBCL9CTNNB1MAPTL3MBTL1 | |
| SCHEMBL11060689 | 0.88 | MGLL (0.61) | MGLLBCL9CTNNB1MAPTL3MBTL1 | |
| SCHEMBL28497167 | 0.86 | MGLL (0.58) | MGLLBCL9CTNNB1MAPTL3MBTL1 | |
| SCHEMBL28120256 | 0.84 | MGLL (0.56) | MGLLBCL9CTNNB1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250361531-A1 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS | AGAIN BIO APS (DK) | 2025-11-27 | — | — | US | disclosed |
| US-12312627-B2 | Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds | GENOMATICA, INC. (US) | 2025-05-27 | — | — | US | disclosed |
| EP-4414451-A2 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4 HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS | Genomatica, Inc. (US) | 2024-08-14 | — | — | EP | disclosed |
| EP-2989113-B1 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS | GENOMATICA INC (US) | 2024-04-10 | — | — | EP | disclosed |
| US-11932845-B2 | Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds | GENOMATICA, INC. (US) | 2024-03-19 | — | — | US | disclosed |
| EP-4321615-A2 | ORGANISMS FOR THE PRODUCTION OF 1,3-BUTANEDIOL | Genomatica, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| EP-3865569-B1 | ORGANISMS FOR THE PRODUCTION OF 1,3-BUTANEDIOL | GENOMATICA INC (US) | 2023-10-04 | — | — | EP | disclosed |
| US-11708589-B2 | Microorganisms for producing 1,3-butanediol and methods related thereto | GENOMATICA INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-20230065295-A1 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS | GENOMATICA INC (US) | 2023-03-02 | — | — | US | disclosed |
| US-11572564-B2 | Microorganisms for producing 1,4-butanediol and methods related thereto | GENOMATICA, INC. (US) | 2023-02-07 | — | — | US | disclosed |
| WO-2010127319-A2 | ORGANISMS FOR THE PRODUCTION OF 1,3-BUTANEDIOL | GENOMATICA, INC. (US) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010127303-A1 | ORGANISMS FOR THE PRODUCTION OF ISOPROPANOL, N-BUTANOL, AND ISOBUTANOL | GENOMATICA, INC. (US) | 2010-11-04 | — | — | WO | disclosed |
| US-20100112654-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL | AGAIN BIO APS (DK) | 2010-05-06 | — | — | US | disclosed |
| WO-2010030711-A2 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL | GENOMATICA, INC. (US) | 2010-03-18 | — | — | WO | disclosed |
| EP-1478760-A4 | ESTERASES WITH LIPASE ACTIVITY | COMMW SCIENT IND RES ORG (AU) | 2005-12-28 | — | — | EP | disclosed |
| US-20050176118-A1 | Esterases with lipase activity | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2005-08-11 | — | — | US | disclosed |
| EP-1478760-A1 | ESTERASES WITH LIPASE ACTIVITY | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003066873-A1 | ESTERASES WITH LIPASE ACTIVITY | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2003-08-14 | — | — | WO | disclosed |
| EP-1002100-A2 | METHOD FOR PRODUCING AND IDENTIFYING NEW HYDROLASES HAVING IMPROVED PROPERTIES | Studiengesellschaft Kohle mbH (DE) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999005288-A2 | METHOD FOR PRODUCING AND IDENTIFYING NEW HYDROLASES HAVING IMPROVED PROPERTIES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1999-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250361531-A1 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS | HSD17B10, HSD17B12, HADHB | MGLL 747/4885BCL9 4776/4885CTNNB1 2456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.