Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4185722 | 1.00 | MAPT (0.42) | MAPTCYP1A2CYP2D6KIF11MEN1 | |
| SCHEMBL2089895 | 0.87 | MAPT (0.43) | MAPTCYP1A2CYP2D6KIF11GRIN2D | |
| SCHEMBL2089897 | 0.87 | MAPT (0.43) | MAPTCYP1A2CYP2D6KIF11GRIN2D | |
| SCHEMBL2089894 | 0.87 | MAPT (0.43) | MAPTCYP1A2CYP2D6KIF11GRIN2D | |
| SCHEMBL6820052 | 0.79 | KIF11 (0.41) | MAPTCYP1A2CYP2D6KIF11MEN1 | |
| SCHEMBL14306296 | 0.78 | KCNN4 (0.43) | MAPTCYP1A2CYP2D6KIF11MEN1 | |
| SCHEMBL4450821 | 0.78 | KCNN4 (0.43) | MAPTCYP1A2CYP2D6KIF11MEN1 | |
| SCHEMBL4943741 | 0.76 | CYP1A2 (0.46) | MAPTCYP1A2CYP2D6KIF11MEN1 | |
| SCHEMBL9037241 | 0.75 | KCNN4 (0.45) | MAPTCYP1A2CYP2D6KIF11MEN1 | |
| SCHEMBL11128706 | 0.75 | KCNN4 (0.45) | MAPTCYP1A2CYP2D6KIF11MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39888-E1 | Process for obtaining quinapryl hydrochloride and solvates useful for isolating and purifying quinapryl hydrochloride | ESTEVE QUIMICA, S.A. (ES) | 2007-10-16 | — | — | US | disclosed |
| WO-2007054966-A2 | A PROCESS FOR THE PREPARATION OF HIGHLY PURE CRYSTALLINE QUINAPRIL HYDROCHLORIDE | AARTI HEALTHCARE LIMITED (IN) | 2007-05-18 | — | — | WO | disclosed |
| EP-1572661-B1 | CRYSTALLINE FORM OF QUINAPRIL HYDROCHLORIDE AND PROCESS FOR PREPARING THE SAME | LUPIN LTD (IN) | 2007-04-25 | — | — | EP | disclosed |
| EP-0992495-B1 | PROCESS FOR OBTAINING QUINAPRYL HYDROCHLORIDE AND SOLVATES USEFUL FOR ISOLATING AND PURIFYING QUINAPRYL HYDROCHLORIDE | ESTEVE QUIMICA SA (ES) | 2004-02-04 | — | — | EP | disclosed |
| EP-0992495-A1 | PROCESS FOR OBTAINING QUINAPRYL HYDROCHLORIDE AND SOLVATES USEFUL FOR ISOLATING AND PURIFYING QUINAPRYL HYDROCHLORIDE | ESTEVE QUIMICA, S.A. (ES) | 2000-04-12 | — | — | EP | disclosed |