Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450821 | 1.00 | KCNN4 (0.43) | KCNN4CYP2C19HIF1ACYP1A2HDAC1 | |
| SCHEMBL17472948 | 0.84 | MEN1 (0.37) | CYP1A2CXCR2KMT2AKIF11MEN1 | |
| SCHEMBL4943741 | 0.83 | CYP1A2 (0.46) | KCNN4CYP2C19HIF1ACYP1A2HDAC1 | |
| SCHEMBL9829581 | 0.81 | CXCR2 (0.42) | KCNN4CYP2C19HIF1ACYP1A2HDAC1 | |
| SCHEMBL9829583 | 0.81 | CXCR2 (0.42) | KCNN4CYP2C19HIF1ACYP1A2HDAC1 | |
| SCHEMBL3937565 | 0.81 | HDAC1 (0.42) | KCNN4CYP2C19HIF1ACYP1A2HDAC1 | |
| SCHEMBL1968290 | 0.81 | ALDH1A1 (0.46) | LMNAL3MBTL1MAPTKMT2AALDH1A1 | |
| SCHEMBL1968289 | 0.81 | ALDH1A1 (0.46) | LMNAL3MBTL1MAPTKMT2AALDH1A1 | |
| SCHEMBL8038268 | 0.80 | ALDH1A1 (0.39) | KCNN4CYP2C19HIF1ACYP1A2HDAC1 | |
| SCHEMBL2089894 | 0.80 | MAPT (0.43) | KCNN4CYP2C19HIF1ACYP1A2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252575-B1 | 2-AMINO-2-PHENYLALKANOL DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | OROXCELL (FR) | 2012-12-19 | — | — | EP | disclosed |