Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310085 | 0.82 | CHRNA7 (0.56) | CHRNA7ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5306566 | 0.81 | SMN1; SMN2 (0.62) | CHRNA7ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL16508652 | 0.81 | CHRNA7 (0.55) | CHRNA7ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL15347856 | 0.79 | CHRNA7 (0.55) | CHRNA7ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL14664078 | 0.78 | ALDH1A1 (0.53) | CHRNA7ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL14828729 | 0.78 | CHRNA7 (0.51) | CHRNA7ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5311984 | 0.77 | SPHK1 (0.52) | CHRNA7ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL845182 | 0.76 | HSD17B10 (0.57) | CHRNA7ALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL13753541 | 0.75 | NPSR1 (0.61) | CHRNA7ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL27879665 | 0.73 | CHRNA7 (0.51) | CHRNA7ALDH1A1SMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039781-A2 | NEW COMPOUNDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2007-04-12 | — | — | WO | disclosed |