Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RHOC | P08134 | 1/20 | 0.44 |
| ▸ | RHOA | P61586 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14648247 | 0.83 | HSD17B10 (0.54) | HSD17B10PTPN2PTPN1POLBCTDSP1 | |
| SCHEMBL845300 | 0.81 | CYP2C9 (0.54) | PTPN2PTPN1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL845267 | 0.81 | RHOC (0.46) | HSD17B10ALDH1A1NPC1CYP2C9CYP2C19 | |
| SCHEMBL845089 | 0.81 | TSHR (0.45) | HSD17B10TDP1ALDH1A1NPC1CYP2C9 | |
| SCHEMBL873200 | 0.80 | RHOC (0.48) | ALDH1A1NPC1CYP2C9CYP2C19MAPT | |
| SCHEMBL2196987 | 0.79 | HSD17B10 (0.50) | HSD17B10PTPN2PTPN1POLBCTDSP1 | |
| SCHEMBL845043 | 0.79 | ALDH1A1 (0.47) | HSD17B10ALDH1A1CYP2C9CYP2C19LMNA | |
| SCHEMBL29106506 | 0.79 | HSD17B10 (0.54) | HSD17B10POLBALDH1A1USP2 | |
| SCHEMBL29106504 | 0.79 | HSD17B10 (0.54) | HSD17B10POLBALDH1A1USP2 | |
| SCHEMBL845205 | 0.79 | ALDH1A1 (0.56) | HSD17B10ALDH1A1CYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |